Plant pathology and applied microbiology

Research unit (PVMA) - sustainable crop protection against pathogens and conservation of biological soil fertility.

The mission of the research unit is the reduction of chemical inputs in agriculture (fungicides and fertilizers), developing low-risk alternatives based on biodegradable molecules, beneficial microorganisms and novel tools for disease prediction and control.

Antifungal products synthetized by microorganisms and plants, beneficial microorganisms (biofungicides, biofertilizers and biostimulants) are studied to find innovative disease control methods. The mode of action and the production protocol are optimized. Moreover, the absence of negative impacts on human health and the environment are investigated.

Sustainable plant protection is also based on the rapid disease prediction and use of optimized agronomic practices. Advanced diagnostic approaches and disease modelling based on molecular methods are developed to predict the risk of emerging or invasive pathogens and to assess the soil microbial quality due to possible changes of climatic conditions and agronomic practices.


Main publications

  • Arrigoni E., Antonielli L., Pindo M., Pertot I., Perazzolli M.(2018). Tissue age and plant genotype affect the microbiota of apple and pear bark. Microbiological Research 211: 57–68 doi: 10.1016/j.micres.2018.04.002
  • Lazazzara V., Bueschl C., Parich A., Pertot I., Schuhmacher R., Perazzolli M. (2018). Downy mildew symptoms on grapevines can be reduced by volatile organic compounds of resistant genotypes. Scientific Reports 8: 1618 doi: 10.1038/s41598-018-19776-2
  • Tomada S., Sonego P., Moretto M., Engelen K., Pertot I., Perazzolli M. and Puopolo G. (2017). Dual RNA-Seq of Lysobacter capsici AZ78 - Phytophthora infestans interaction shows the implementation of attack strategies by the bacterium and unsuccessful oomycete defense responses. Environmental Microbiology 19: 4113–4125 doi: 10.1111/1462-2920.13861
  • Lazazzara V., Perazzolli M., Pertot I., Biasioli F., Puopolo P., Cappellin L. (2017). Growth media affect the volatilome and antimicrobial activity against Phytophthora infestans in four Lysobacter type strains. Microbiological Research 201: 52–62 doi: 10.1016/j.micres.2017.04.015
  • Perazzolli M., Herrero N. Sterck L., Lenzi L., Pellegrini A., Puopolo G., Van de Peer Y. and Pertot I. (2016). Transcriptomic responses of a simplified soil microcosm to a plant pathogen and its biocontrol agent reveals a complex reaction to the harsh habitat. BMC Genomics 17:838 doi: 10.1186/s12864-016-3174-4
  • Tomada S., Puopolo G., Perazzolli M., Musetti R. Loi N., Pertot I. (2016). Pea broth enhances the biocontrol efficacy of Lysobacter capsici AZ78 by triggering cell motility associated with biogenesis of type IV pilus. Frontiers in Microbiology 7:1136 doi: 10.3389/fmicb.2016.01136
  • Cappelletti M., Perazzolli M., Antonielli L., Nesler A., Torboli E., Bianchedi P.L., Pindo M., Puopolo G. and Pertot I. (2016). Leaf treatments with a protein-based resistance inducer partially modify phyllosphere microbial communities of grapevine. Frontiers in Plant Science 7:1053 doi: 10.3389/fpls.2016.01053
  • Perazzolli M., Palmieri M.C., MataforaV., Bachi A. and Pertot I. (2016). Phosphoproteomic analysis of induced resistance reveals activation of signal transduction processes by beneficial and pathogenic interaction in grapevine. Journal of Plant Physiology 195: 59–72 doi: 10.1016/j.jplph.2016.03.007
  • Puopolo G., Tomada S., Sonego P., Moretto M., , Engelen K., Perazzolli M. and Pertot I. (2016). The Lysobacter capsici AZ78 genome has a gene pool enabling it to interact successfully with phytopathogenic microorganisms and environmental factors. Frontiers in Microbiology 7: 96 doi: 10.3389/fmicb.2016.00096
  • Lenzi L., Caruso C., Bianchedi P.G., Pertot I. and Perazzolli M.+ (2016). Laser microdissection of grapevine leaves reveals site-specific regulation of transcriptional response to Plasmopara viticola. Plant and Cell Physiology 57:69-81 doi: 10.1093/pcp/pcv166
  • Nesler A., Perazzolli M., Puopolo G., Giovannini O., Elad Y. and Pertot I. (2015). A complex protein derivative acts as biogenic elicitor of grapevine resistance against powdery mildew under field conditions. Frontiers In Plant Science 6: 715 doi: 10.3389/fpls.2015.00715
  • Perazzolli M., Antonielli L., Storari M., Puopolo G., Pancher M., Giovannini O., Pindo M. and Pertot I. (2014). Resilience of the natural phyllosphere microbiota of the grapevine to chemical and biological pesticides. Applied and Environmental Microbiology 80: 3585-96 doi: 10.1128/AEM.00415-14
  • Banani H., Roatti B., Ezzahi B., Gessler C., Pertot I. and Perazzolli M. (2014). Characterization of resistance mechanisms activated by Trichoderma harzianum T39 and benzothiadiazole to downy mildew in different grapevine cultivars. Plant Pathology 63: 334–343 DOI: 10.1111/ppa.12089



  • INTERFUTURE  - From microbial interactions to new-concept biopesticides and biofertilizers - H2020 Marie Sklodowska-Curie Innovative Training Network (MSCA-ITN-EID)
  • RELACS  - Replacement of contentious inputs in organic farming systems - H2020 Research and Innovation Programme
  • RhizoTalk (Ana Bejarano Ramos ) - Decrypting the role of bacterial signals in microbial interactions to enhance Lysobacter establishment in the rhizosphere – H2020 Marie Skłodowska-Curie Individual Fellowship (H2020-MSCA-IF)
  • MePS - Sustainable orchard - Autonomous Province of Trento’s ‘Programma di Sviluppo Rurale 2014-2020’ within the framework of the European Innovation Partnership ‘Agricultural Productivity and Sustainability’

Person in charge


Name Phone Mobile Email
GERARDO PUOPOLO (ResearchGate profile) 0461615502